About the body's immune system to protect the system can be divided into three lines of defense, the first by a wide range of skin and epithelial cells, pathogens can be made on the outside symptoms of hypothyroidism of physical isolation; second produced by macrophages, addicted neutrophils, monocytes, natural killer cells composed of such non-specific immune response; the third to take over by the specific immune system, such as T cells, B cells, these cells produce a series of the antibodies come with pathogen antigen binding to decreased activity or allow other immune cells to attack them. Specificity of the immune system, maintain the memory of the target antigen, symptoms of hypothyroidism and autoimmune diseases belonging to specific immunity, it will repeatedly attack itself. Classification of autoimmune diseases autoimmune symptoms of hypothyroidism disease that may affect any part of the body, according to their target of attack can be divided into two categories: 1. Organ-specific autoimmune diseases (organ-specific autoimmune disease): from antibodies to a single organ or gland as an attack target specific target antigen, so only a single organ or gland function will be to stimulate or inhibit autoantibodies produce inflammation, triggering lesions. This type of diseases are: Addison's disease (Addison's Disease), symptoms of hypothyroidism autoimmune symptoms of hypothyroidism anemia (Autoimmune anemia), 古德巴斯德 syndrome (Goodpasture's syndrome), Hashimoto's thyroiditis (Hashimoto's thyroiditis), insulin-dependent diabetes (Insulin-dependent diabetes mellitus), Graves's disease (Grave's disease), myasthenia gravis (myasthenia gravis), autoimmune hepatitis symptoms of hypothyroidism (autoimmune hepatitis) and so on. (2) systemic autoimmune disease (Systemic autoimmune disease): Systemic effects on a wide range of target symptoms of hypothyroidism antigens, causing systemic tissue damage, leading to multiple organ and tissue inflammatory diseases. This type of disease: systemic lupus erythematosus (systemic lupus erythematosus, SLE) rheumatoid arthritis (Rheumatoid arthritis, RA) cell repair even syndrome (Sjogren's syndrome) Multiple symptoms of hypothyroidism Sclerosis (Multiple sclerosis) ankylosing spondylitis ( ankylosing spondylitis, AS) and so on.
Symptoms of autoimmune symptoms of hypothyroidism disease autoimmune disease characterized by inflammation that can cause swelling, fever, pain and swelling. And the incidence of autoimmune attack symptoms depend on the part of the body, such as: when the attack joints such as rheumatoid arthritis, may be joint pain, stiffness, deformation, loss of function; if it affects the thyroid, such as Graves's disease and thyroiditis may lead to fatigue, symptoms of hypothyroidism weight gain, muscle pain and other symptoms; if it attacks the skin, such as multiple sclerosis, systemic lupus erythematosus, it will cause a rash, blisters and color changes. Many autoimmune diseases, and will not be limited symptoms of hypothyroidism to a certain part of the body, for example, lupus affects the skin, joints, kidneys, heart, nerves, blood vessels or more places. So if unexplained fever, hair loss, mouth ulcers, joint pain, joint stiffness, back pain, muscle weakness, rash, proteinuria, hematuria, purpura, poor circulation, dry eyes, dry mouth, etc., the two three or more symptoms exist, it is recommended symptoms of hypothyroidism to find Rheumatology examination. The causes of autoimmune diseases in the current study, a single cause enough to cause symptoms symptoms of hypothyroidism appear, a variety of gene types in vivo conditions and random interaction between environmental risk factors, be possible to trigger the disease. Autoimmune symptoms of hypothyroidism diseases, high-risk groups are: Immune system disorders: B lymphocytes (white blood cells) abnormal and the abnormal antibodies that attack its own cells genetic: in first-degree relatives in autoimmune diseases, their blood appear autoimmune antibody positive rate will increase, in some specific factor stimulation, it is easy to cause the immune system is out of control environment: in particular, the virus infection is considered symptoms of hypothyroidism the most likely cause; Additionally, symptoms of hypothyroidism drugs, radiation, smoking, damage caused by environmental toxins may also induce symptoms of hypothyroidism hormones such diseases: Many autoimmune diseases are more common in women. Animal experiments found that estrogen (estrogen) can enhance the formation of anti-DNA symptoms of hypothyroidism antibodies and increase the severity symptoms of hypothyroidism of kidney disease. General use of contraceptives containing estrogen may also make lupus worse. Autoimmune diseases, autoimmune diseases, detecting a wide range of laboratory examination content is also very extensive, most of the diagnostic methods are as follows: history and clinical characterization of hematology testing: Is there anemia, leukocytosis, and abnormal lymphocyte phenomenon, CRP (C-reactive protein) is increased, we can see whether there is infection or inflammation ongoing immunological detection: detection of autoantibodies symptoms of hypothyroidism such as anti-nuclear antibody (anti-nuclear antibody, ANA); immune complexes (immune complex, IC) detection, such as rheumatoid factor (rheumatoid factor, RF); immune response testing ADM autoimmune antibody test chip: Currently still experimental autoimmune diseases traditionally treat autoimmune diseases, mainly symptoms of hypothyroidism drugs are analgesics, steroids, immunomodulators, immunosuppressive symptoms of hypothyroidism agents. Non-steroidal anti-inflammatory drugs: mainly used to treat musculoskeletal symptoms of hypothyroidism symptoms, mild serositis, and physical symptoms such as fever. symptoms of hypothyroidism The side effects of these drugs include gastrointestinal bleeding, renal abnormalities. Immunosuppressive Drugs: Commonly used azathioprine, chlorambucil, cyclophosphamide, cyclosporine, mycophenolate and methotrexate. However, these drugs can weaken the body's ability to resist foreign invaders, including symptoms of hypothyroidism the microbes that cause infections and cancer cells. Corticosteroids: such as oral prednisone, can relieve inflammation and suppress the immune system. Long-term use have many side effects. With immunology, molecular biology and genetic engineering advances, scientists have designed a variety of biological agents to target immune-based therapies, such as missiles can be aimed precisely as abnormal immune molecules, and these targeted therapies can be divided into four categories : 1. Anti-cytokine therapy symptoms of hypothyroidism (anti-cytokine therapy) symptoms of hypothyroidism 2. anti-B cell therapy (B cell depletion therapy) 3. anti-T cell therapy (T cell depletion therapy) 4. immune tolerance induction therapy (tolerance induction therapy) but the greatest of these categories of drugs are very expensive and limited, while the former two types of health insurance to be paid only conditional symptoms of hypothyroidism severe refractory rheumatoid arthritis, the latter two are still in large-scale clinical trials. How to prevent autoimmune disease if there is a family history of autoimmune diseases, with special attention to avoid triggering. If necessary, there may also be specific genetic blood testing, antibody normal daily routine, a balanced diet, regular exercise, adequate symptoms of hypothyroidism sleep attention to blood pressure, blood lipids, blood glucose and appropriate weight loss quitting: At present, studies have shown that smoking increases the risk of systemic the risk of systemic lupus erythematosus fish oil intake: The study found that a diet low Omega-3 levels plus high levels of Omega-6, creating a modern constitution inflammation, increase the risk of autoimmune disease probability; research has also pointed out that the supplement Omega-3 fatty acids can reduce inflammation, symptoms of hypothyroidism relieve rheumatoid arthritis associated with pain and stiffness. Omega-3 fatty acids, the main sources of anchovies, blue fish, herring, mackerel, salmon (wild salmon than farmed containing more Omega-3), sardines, sturgeon, gray trout, and tuna fish; Omega-6 fatty acids, mainly from corn oil, soybean oil, and red meat. Enough vitamin symptoms of hypothyroidism D: studies have found that vitamin D the body there are more people symptoms of hypothyroidism who are less likely to have type 1 diabetes, multiple sclerosis and other autoimmune diseases. In addition to often in outdoor symptoms of hypothyroidism activities, so that the outer skin to synthesize vitamin D, cod liver oil, fish containing high fat (such as wild salmon, tuna or mackerel), and marine animals, such as the liver, but also get the vitamin D sources. Less oil, less calories: high-fat, high-calorie diet, the body's inflammatory substances will more easily induced autoimmune diseases. Do not eat will change the immunity drugs, foods to relieve stress: Stress does induce autoimmune diseases, the incidence of people who have been, stress hormones may worsen inflammation worse. Try to avoid exposure to environmental pollutants and heavy metals
2013 (68) September (8) August (4) July (3) June (4) May (8) April (5) March (12) autoimmune diseases (Autoimmune disease) man fat hidden behind the crisis in middle-aged men's seven major health risks!! relaxed attractive man playing badminton sports injury prevention prevention of computer vision syndrome (Computer Vision symptoms of hypothyroidism Syndrome) prevention of falls who love to dig earwax to pay attention Oh! movement and minus
No comments:
Post a Comment