The incidence of the disease after 50 years of universal vaccination, which is comparable with that at the start, granuloma annulare it's not a good sign for vaccination. Under the motto "If it does not work, let's more" was introduced 4 years ago booster 10-year-old children, and vaccination is offered to adults as well.
Note that in 2009, it was reported more than 800 cases, but so far the media haunted, haunted as now. Also interesting is the decline in 2010-2011, which could be due to the newly introduced 10-year booster. As you can see, it did not last too long.
That would be about 200 additional cases per 10 million inhabitants mean the difference? Even larger increase occurred between 2008 and 2009, yet can not remember such a media massage. What could cause a difference in the approach of the media? That would decline vaccination coverage, still less willing granuloma annulare parents to vaccinate their children? However, in comparison with 2009 coverage actually increased thanks to a new vaccination coverage granuloma annulare of 10-year-olds. Vaccine protection is therefore, according to the official views of these children was extended to 10 years, which outweigh decline in vaccination rates in young children.
U whooping cough can see that even in the period when inoculated against it across the board, its occurrence was fluctuating. The disease granuloma annulare has its own natural cycle and its incidence varies granuloma annulare regardless of the constant coverage. The sharp rise in the past few years, but will have a different cause.
Against whooping cough to vaccinate roughly flat from the 50s of the 20th century. All those years were seeded only children, the last dose of each of us got in 5 years. Still, after all these years, the incidence basically stable, with small ripples natural fluctuations. Why was it changed?
A possible reason for the transition to an acellular vaccine, which since 2007 vaccinate all children, before this year only children whose parents paid hexa. Whole-cell vaccine had a more acute adverse reactions, but it seems to be more effective. According to an analysis of epidemics granuloma annulare by age groups, older children had better granuloma annulare protection than younger. [1]
Bordetella pertussis after colonization of the airways produces substances that prevent the immune system granuloma annulare to recognize it and fight against it. Only after about 2 weeks will make antibodies against these substances, and will effectively eliminate bacteria. Innate immunity thus contains antibodies against these toxins. In the second contact efficacy individual who has suffered it, the bacteria immediately recognize and destroy granuloma annulare it quickly. Therefore there nepropukne disease and is not infectious or very short time. [2]
Acellular vaccines contain this toxin antigen, granuloma annulare so after vaccination against it does not produce antibodies. After vaccination also does not produce mucosal antibodies - IgA. When infection vaccinated whooping cough in terms of the spread of infection granuloma annulare occurs as a primary infection in unvaccinated. The patient is colonized Bordetella which it can multiply and spread it to the surroundings. He may or may not have symptoms.
A milder form of the disease with atypical symptoms in vaccinated is indeed more pleasant for themselves, but risky for the environment granuloma annulare because they become vectors. Their disease is often not recognized correctly and hides under various diagnoses such as asthma. It has been demonstrated that vaccination may distribute whooping cough and disperse it. [3] She is known to take place when the child vaccinated infected unvaccinated granuloma annulare younger siblings.
A recent study conducted by the FDA for young baboon, [4] showed that chicks vaccinated acellular vaccine, compared with calves vaccinated with whole cell vaccine, getting rid of the infection and also more evidence of transmission of pertussis from vaccinated to unvaccinated individuals. Dr. Erik Hewlett from the University of Virginia, who was not involved granuloma annulare in the study, granuloma annulare but worked with one of the authors, told the Washington Post: [5]
Maybe you've heard of cocoons strategy, ie. Vaccinating persons close to the one you want to protect, but can not be vaccinated. This strategy is, after all, the foundation of collective immunity and the main argument for mandatory vaccination: restrictions to the circulation of the pathogen population in the vast majority of vaccine were protected individuals who for some reason can not be vaccinated. As mentioned study proves the assumption that subjects do not spread disease, is incorrect.
The study showed that baboons, whole cell vaccine inoculations, the author managed to get rid of whooping cough in about half the time than individuals vaccinated with acellular vaccine. It was about 18 resp. 35 days. As it is, although vaccination will protect against infection manifest, granuloma annulare but at the same time will make you symptomless vectors.
It is strange that in an appeal granuloma annulare to strengthen vaccination appears explanation pr
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