Serological conflict, diabet otherwise known as hemolytic disease of the newborn is a disease which

Serological conflict, diabet otherwise known as hemolytic disease of the newborn is a disease which is due to an immune reaction between antibodies and antigens maternal fetal blood cells. This disease, which occurs as a result of a conflict of serological is a complex process, which results in the breakdown of fetal red blood cells (ie, hemolysis). It is a disease that affects only the fetus, the mother does not feel any of the symptoms. Serological conflict - the definition of conflict of serological basis is therefore incompatible blood factors between mother and child. Man has one of the four blood groups - A, B, AB or 0. In addition, there are some characteristic of Rh. You should know that not every person has the characteristic of Rh, then we deal with the so-called. Rh feature. It is non-compliance with regard to the characteristics of Rh is the most common reason for the appearance of a conflict of serological. It works in such a way that if the mother does not have the characteristics of Rh, and a child who wears his father's belly is characteristic of Rh, is among these factors diabet creates a mismatch. As a result, the mother cells are sensitized to their child, and her body produced antibodies to blood cells to combat child. This process is absolutely ignorant, results only from the specific activity of the human body. The antibodies produced in the mother's blood passes to the fetus and partially damage the cells through their clumping and decay.
The mechanism of action of serological conflict can be compared to the body's defense against viruses. Shaped diabet in the mother's body resistance, which aims to eradicate the intruder. In this case, however, such immune activity is by all means disadvantage because disease causes the child. Serological conflict in most cases is caused by the mismatch within the characteristics of Rh, but there are also conflicts caused by mismatch within a main blood groups (this kind of conflict are found in about 10% of all pregnancies). This conflict is most common in the system: the mother - a group 0 child - blood group A. As a result, formed in the mother's blood cells immune antibodies to combat child. The effects of this process are similar to those in the case of non-compliance within the Rh factor, but it is far less dangerous conflict and less common.
Serological conflict - Effects There are three clinical forms of conflict serological: 1. Overall swelling of the fetus - the most severe form of the disease is observed in the swelling of the skin and subcutaneous tissue, often also petechiae bleeding and abdominal fetal liquid accumulates przesiękowy. As a result of these problems, diabet compounded anemia, are often circulatory failure, fetal death, and his death after birth. 2. Severe hemolytic diabet jaundice - a newborn diabet child shows signs of jaundice or jaundice occurs in the first period of his life, and has a strong run. If serological conflict is not treated, it can lead to the accumulation of indirect bilirubin, which is a chemical compound formed by the breakdown of heme. There is a danger that starts bilirubin pass through the vascular barrier - brain, consequently leading to hepatitis diabet basal ganglia and damage to the brain. For proper treatment serological conflict there is no greater risk that the brain is damaged. Hemolytic jaundice causes enlargement diabet of the spleen and liver, also diagnosed with petechiae on the skin of the fetus. 3. Acute anemia, or anemia. In less severe cases revealed anemia, diabet which may occur after even a few weeks after birth, this is due to the persistence of sizeable antibody diabet levels, it can take up to 6 weeks. But if we are dealing diabet with severe anemia, born child will have an enlarged liver, spleen and pale, waxy skin tone. In addition, there may be Przesieka the serous cavities of the body.
Conflict HIV - Treatment Treatment of complications caused by serological conflict can lead both in utero and after birth. During pregnancy, it depends on the child hauled diabet him umbilical cord blood directly, this is done under the control of ultrasound equipment, such as transfusions, if necessary, can be repeated. After the birth of a child is to phototherapy treatment (in case of jaundice), or illumination lamps, sometimes also require a blood transfusion. In the current era of serological conflicts diabet occur relatively rarely. This is due to the fact that women oo Rh negative trait is given a special form of the immunoglobulin, which neutralizes the fetal cells getting into the maternal blood. The immunoglobulin should also be given to all mothers who are Rh negative within 72 hours after birth. This is due to the fact that during diabet labor and delivery fetal cells often get into the mother's circulatory system. Stano